Alice Chan, MD, PhD

Assistant Adjunct Professor
Diabetes Center

Alice is originally from Texas. She did her undergraduate at UT Austin and then went to UT Southwestern for the MD/PhD program. She was in Ward Wakeland's lab at UTSW studying SLAM family members in a mouse model of SLE. She moved to San Francisco for pediatric residency at UCSF and stayed on to pursue fellowships in both pediatric rheumatology and allergy/immunology. In her free time, you will find her baking or eating around town looking for the best food.

Publications: 

Discovery of stimulation-responsive immune enhancers with CRISPR activation.

Nature

Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A

Exome Sequencing Reveals Mutations in AIRE as a Cause of Isolated Hypoparathyroidism.

The Journal of clinical endocrinology and metabolism

Li D, Streeten EA, Chan A, Lwin W, Tian L, Pellegrino da Silva R, Kim CE, Anderson MS, Hakonarson H, Levine MA

Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders.

The Journal of allergy and clinical immunology

Stray-Pedersen A, Sorte HS, Samarakoon P, Gambin T, Chinn IK, Coban Akdemir ZH, Erichsen HC, Forbes LR, Gu S, Yuan B, Jhangiani SN, Muzny DM, Rødningen OK, Sheng Y, Nicholas SK, Noroski LM, Seeborg FO, Davis CM, Canter DL, Mace EM, Vece TJ, Allen CE, Abhyankar HA, Boone PM, Beck CR, Wiszniewski W, Fevang B, Aukrust P, Tjønnfjord GE, Gedde-Dahl T, Hjorth-Hansen H, Dybedal I, Nordøy I, Jørgensen SF, Abrahamsen TG, Øverland T, Bechensteen AG, Skogen V, Osnes LT, Kulseth MA, Prescott TE, Rustad CF, Heimdal KR, Belmont JW, Rider NL, Chinen J, Cao TN, Smith EA, Caldirola MS, Bezrodnik L, Lugo Reyes SO, Espinosa Rosales FJ, Guerrero-Cursaru ND, Pedroza LA, Poli CM, Franco JL, Trujillo Vargas CM, Aldave Becerra JC, Wright N, Issekutz TB, Issekutz AC, Abbott J, Caldwell JW, Bayer DK, Chan AY, Aiuti A, Cancrini C, Holmberg E, West C, Burstedt M, Karaca E, Yesil G, Artac H, Bayram Y, Atik MM, Eldomery MK, Ehlayel MS, Jolles S, Flatø B, Bertuch AA, Hanson IC, Zhang VW, Wong LJ, Hu J, Walkiewicz M, Yang Y, Eng CM, Boerwinkle E, Gibbs RA, Shearer WT, Lyle R, Orange JS, Lupski JR

A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.

The Journal of experimental medicine

Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Fu SM, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM

Central tolerance to self revealed by the autoimmune regulator.

Annals of the New York Academy of Sciences

Chan AY, Anderson MS

B cell-intrinsic CD84 and Ly108 maintain germinal center B cell tolerance.

Journal of immunology (Baltimore, Md. : 1950)

Wong EB, Soni C, Chan AY, Domeier PP

Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation.

Journal of clinical immunology

Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM

Treatment of juvenile idiopathic arthritis.

Pediatric annals

Chan AY, Milojevic D

Early vs. delayed diagnosis of severe combined immunodeficiency: a family perspective survey.

Clinical immunology (Orlando, Fla.)

Chan A, Scalchunes C, Boyle M, Puck JM

Antigen-specific responses and ANA production in B6.Sle1b mice: a role for SAP.

Journal of autoimmunity

Jennings P, Chan A, Schwartzberg P, Wakeland EK, Yuan D

The role of SAP and the SLAM family in autoimmunity.

Current opinion in immunology

Chan AY, Westcott JM, Mooney JM, Wakeland EK, Schatzle JD

Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.

Immunity

Wandstrat AE, Nguyen C, Limaye N, Chan AY, Subramanian S, Tian XH, Yim YS, Pertsemlidis A, Garner HR, Morel L, Wakeland EK