Welcome to the Anderson Lab
Our group is broadly interested in understanding how immune tolerance is controlled and its relationship to autoimmune diseases. Please feel free to explore our website to learn more.
Shown below is immunostaining of a collection of thymic medullary epithelial cells (mTEC's) stained for Aire in green and a fate map RFP reporter in red. We recently described this powerful genetic tracing tool in Metzger et al. Cell Reports, 5:166, 2013. Such tools allow us to further define the key populations in the thymus that help enforce self-tolerance to the developing T cell repertoire.