Publications

  • Warshauer JT, Bluestone JA, Anderson MS. New Frontiers in the Treatment of Type 1 Diabetes. Cell Metab. 2020 Jan 7;31(1):46-61. doi: 10.1016/j.cmet.2019.11.017. Epub 2019 Dec 12. Review. PMID:31839487 | PMCID:PMC6986815
  • Battaglia M, Ahmed S, Anderson MS, Atkinson MA, Becker D, Bingley PJ, Bosi E, Brusko TM, DiMeglio LA, Evans-Molina C, Gitelman SE, Greenbaum CJ, Gottlieb PA, Herold KC, Hessner MJ, Knip M, Jacobsen L, Krischer JP, Long SA, Lundgren M, McKinney EF, Morgan NG, et al. Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes. Diabetes Care. 2020 Jan;43(1):5-12. doi: 10.2337/dc19-0880. Epub 2019 Nov 21. PMID:31753960 | PMCID:PMC6925574
  • Calderon D, Nguyen MLT, Mezger A, Kathiria A, Müller F, Nguyen V, Lescano N, Wu B, Trombetta J, Ribado JV, Knowles DA, Gao Z, Blaeschke F, Parent AV, Burt TD, Anderson MS, Criswell LA, Greenleaf WJ, Marson A, Pritchard JK. Landscape of stimulation-responsive chromatin across diverse human immune cells. Nat Genet. 2019 Oct;51(10):1494-1505. doi: 10.1038/s41588-019-0505-9. Epub 2019 Sep 30. PMID:31570894 | PMCID:PMC6858557
  • Moore PC, Cortez JT, Chamberlain CE, Alba D, Berger AC, Quandt Z, Chan A, Cheng MH, Bautista JL, Peng J, German MS, Anderson MS, Oakes SA. Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. J Clin Invest. 2019 Aug 1;130:4676-4681. doi: 10.1172/JCI129961. PMID:31369399 | PMCID:PMC6819098
  • Landegren N, Rosen LB, Freyhult E, Eriksson D, Fall T, Smith G, Ferre EMN, Brodin P, Sharon D, Snyder M, Lionakis M, Anderson M, Kämpe O. Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'. Elife. 2019 Jun 27;8. pii: e43578. doi: 10.7554/eLife.43578. PMID:31244471 | PMCID:PMC6597240
  • Sin JH, Zuckerman C, Cortez JT, Eckalbar WL, Erle DJ, Anderson MS, Waterfield MR. The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses. J Exp Med. 2019 Sep 2;216(9):2024-2037. doi: 10.1084/jem.20182316. Epub 2019 Jun 19. PMID:31217192 | PMCID:PMC6719416
  • Eriksson D, Bacchetta R, Gunnarsson HI, Chan A, Barzaghi F, Ehl S, Hallgren Å, van Gool F, Sardh F, Lundqvist C, Laakso SM, Rönnblom A, Ekwall O, Mäkitie O, Bensing S, Husebye ES, Anderson M, Kämpe O, Landegren N. The autoimmune targets in IPEX are dominated by gut epithelial proteins. J Allergy Clin Immunol. 2019 Jul;144(1):327-330.e8. doi: 10.1016/j.jaci.2019.02.031. Epub 2019 Apr 23. No abstract available. PMID:31027649
  • Van Gool F, Nguyen MLT, Mumbach MR, Satpathy AT, Rosenthal WL, Giacometti S, Le DT, Liu W, Brusko TM, Anderson MS, Rudensky AY, Marson A, Chang HY, Bluestone JA. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. 2019 Feb 19;50(2):362-377.e6. doi: 10.1016/j.immuni.2018.12.016. Epub 2019 Jan 29. PMID:30709738 | PMCID:PMC6476426
  • Fergusson JR, Morgan MD, Bruchard M, Huitema L, Heesters BA, van Unen V, van Hamburg JP, van der Wel NN, Picavet D, Koning F, Tas SW, Anderson MS, Marioni JC, Holländer GA, Spits H. Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens. Front Immunol. 2019 Jan 14;9:2902. doi: 10.3389/fimmu.2018.02902. eCollection 2018. PMID:30692988 | PMCID:PMC6340304
  • Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, et al. Thymic regulatory T cells arise via two distinct developmental programs. Nat Immunol. 2019 Feb;20(2):195-205. doi: 10.1038/s41590-018-0289-6. Epub 2019 Jan 14. PMID:30643267 | PMCID:PMC6650268
  • Redondo MJ, Steck AK, Sosenko J, Anderson M, Antinozzi P, Michels A, Wentworth JM, Atkinson MA, Pugliese A, Geyer S; Type 1 Diabetes TrialNet Study Group.. Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes. Diabetes Care. 2018 Dec;41(12):2480-2486. doi: 10.2337/dc18-0861. Epub 2018 Oct 1. PMID:30275285 | PMCID:PMC6245213
  • Wan X, Zinselmeyer BH, Zakharov PN, Vomund AN, Taniguchi R, Santambrogio L, Anderson MS, Lichti CF, Unanue ER. Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides. Nature. 2018 Aug;560(7716):107-111. doi: 10.1038/s41586-018-0341-6. Epub 2018 Jul 18. PMID:30022165 | PMCID:PMC6090537
  • Miller CN, Proekt I, von Moltke J, Wells KL, Rajpurkar AR, Wang H, Rattay K, Khan IS, Metzger TC, Pollack JL, Fries AC, Lwin WW, Wigton EJ, Parent AV, Kyewski B, Erle DJ, Hogquist KA, Steinmetz LM, Locksley RM, Anderson MS. Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development. Nature. 2018 Jul;559(7715):627-631. doi: 10.1038/s41586-018-0345-2. Epub 2018 Jul 18. PMID:30022164 | PMCID:PMC6062473
  • Husebye ES, Anderson MS, Kämpe O. Autoimmune Polyendocrine Syndromes. N Engl J Med. 2018 Jun 28;378(26):2543-2544. doi: 10.1056/NEJMc1805308. No abstract available. PMID:29949487
  • Stamatouli AM, Quandt Z, Perdigoto AL, Clark PL, Kluger H, Weiss SA, Gettinger S, Sznol M, Young A, Rushakoff R, Lee J, Bluestone JA, Anderson M, Herold KC. Collateral Damage: Insulin-Dependent Diabetes Induced With Checkpoint Inhibitors. Diabetes. 2018 Aug;67(8):1471-1480. doi: 10.2337/dbi18-0002. Epub 2018 Jun 24. Review. PMID:29937434 | PMCID:PMC6054443
  • Cheng M, Anderson MS. Thymic tolerance as a key brake on autoimmunity. Nat Immunol. 2018 Jul;19(7):659-664. doi: 10.1038/s41590-018-0128-9. Epub 2018 Jun 20. Review. PMID:29925986 | PMCID:PMC6370479
  • Perry JSA, Russler-Germain EV, Zhou YW, Purtha W, Cooper ML, Choi J, Schroeder MA, Salazar V, Egawa T, Lee BC, Abumrad NA, Kim BS, Anderson MS, DiPersio JF, Hsieh CS. Transfer of Cell-Surface Antigens by Scavenger Receptor CD36 Promotes Thymic Regulatory T Cell Receptor Repertoire Development and Allo-tolerance. Immunity. 2018 May 15;48(5):923-936.e4. doi: 10.1016/j.immuni.2018.04.007. Epub 2018 May 8. Erratum in: Immunity. 2018 Jun 19;48(6):1271. PMID:29752065 | PMCID:PMC5986080
  • Spence A, Purtha W, Tam J, Dong S, Kim Y, Ju CH, Sterling T, Nakayama M, Robinson WH, Bluestone JA, Anderson MS, Tang Q. Revealing the specificity of regulatory T cells in murine autoimmune diabetes. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5265-5270. doi: 10.1073/pnas.1715590115. Epub 2018 Apr 30. Erratum in: Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5634. PMID:29712852 | PMCID:PMC5960284
  • Husebye ES, Anderson MS, Kämpe O. Autoimmune Polyendocrine Syndromes. N Engl J Med. 2018 Mar 22;378(12):1132-1141. doi: 10.1056/NEJMra1713301. Review. No abstract available. PMID:29562162 | PMCID:PMC6007870
  • Cepeda S, Cantu C, Orozco S, Xiao Y, Brown Z, Semwal MK, Venables T, Anderson MS, Griffith AV. Age-Associated Decline in Thymic B Cell Expression of Aire and Aire-Dependent Self-Antigens. Cell Rep. 2018 Jan 30;22(5):1276-1287. doi: 10.1016/j.celrep.2018.01.015. PMID:29386114 | PMCID:PMC5813500
  • Abbott JK, Huoh YS, Reynolds PR, Yu L, Rewers M, Reddy M, Anderson MS, Hur S, Gelfand EW. Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE). J Autoimmun. 2018 Mar;88:114-120. doi: 10.1016/j.jaut.2017.10.010. Epub 2017 Nov 10. PMID:29129473 | PMCID:PMC5846191
  • Proekt I, Miller CN, Lionakis MS, Anderson MS. Insights into immune tolerance from AIRE deficiency. Curr Opin Immunol. 2017 Dec;49:71-78. doi: 10.1016/j.coi.2017.10.003. Epub 2017 Oct 21. Review. PMID:29065385 | PMCID:PMC5705335
  • Li D, Streeten EA, Chan A, Lwin W, Tian L, Pellegrino da Silva R, Kim CE, Anderson MS, Hakonarson H, Levine MA. Exome Sequencing Reveals Mutations in AIRE as a Cause of Isolated Hypoparathyroidism. J Clin Endocrinol Metab. 2017 May 1;102(5):1726-1733. doi: 10.1210/jc.2016-3836. PMID:28323927 | PMCID:PMC5443324
  • Proekt I, Miller CN, Jeanne M, Fasano KJ, Moon JJ, Lowell CA, Gould DB, Anderson MS, DeFranco AL. LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity. J Clin Invest. 2016 Oct 3;126(10):3758-3771. doi: 10.1172/JCI84440. Epub 2016 Aug 29. PMID:27571405 | PMCID:PMC5087700
  • Landegren N, Pourmousa Lindberg M, Skov J, Hallgren Å, Eriksson D, Lisberg Toft-Bertelsen T, MacAulay N, Hagforsen E, Räisänen-Sokolowski A, Saha H, Nilsson T, Nordmark G, Ohlsson S, Gustafsson J, Husebye ES, Larsson E, Anderson MS, Perheentupa J, Rorsman F, Fenton RA, Kämpe O. Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis. J Am Soc Nephrol. 2016 Oct;27(10):3220-3228. Epub 2016 Mar 16. PMID:26984885 | PMCID:PMC5042672
  • Anderson MS, Su MA. AIRE expands: new roles in immune tolerance and beyond. Nat Rev Immunol. 2016 Apr;16(4):247-58. doi: 10.1038/nri.2016.9. Epub 2016 Mar 14. Review. PMID:26972725 | PMCID:PMC4831132
  • Landegren N, Sharon D, Freyhult E, Hallgren Å, Eriksson D, Edqvist PH, Bensing S, Wahlberg J, Nelson LM, Gustafsson J, Husebye ES, Anderson MS, Snyder M, Kämpe O. Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1. Sci Rep. 2016 Feb 1;6:20104. doi: 10.1038/srep20104. PMID:26830021 | PMCID:PMC4735587
  • Malhotra D, Linehan JL, Dileepan T, Lee YJ, Purtha WE, Lu JV, Nelson RW, Fife BT, Orr HT, Anderson MS, Hogquist KA, Jenkins MK. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nat Immunol. 2016 Feb;17(2):187-95. doi: 10.1038/ni.3327. Epub 2016 Jan 4. PMID:26726812 | PMCID:PMC4718891
  • Chan AY, Anderson MS. Central tolerance to self revealed by the autoimmune regulator. Ann N Y Acad Sci. 2015 Nov;1356:80-9. doi: 10.1111/nyas.12960. Review. PMID:26579596 | PMCID:PMC4654700
  • LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS. Identification of a novel cis-regulatory element essential for immune tolerance. J Exp Med. 2015 Nov 16;212(12):1993-2002. doi: 10.1084/jem.20151069. Epub 2015 Nov 2. PMID:26527800 | PMCID:PMC4647269
  • Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):E4448-57. doi: 10.1073/pnas.1512081112. Epub 2015 Jul 27. PMID:26216992 | PMCID:PMC4538633
  • Landegren N, Sharon D, Shum AK, Khan IS, Fasano KJ, Hallgren Å, Kampf C, Freyhult E, Ardesjö-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, et al. Transglutaminase 4 as a prostate autoantigen in male subfertility. Sci Transl Med. 2015 Jun 17;7(292):292ra101. doi: 10.1126/scitranslmed.aaa9186. PMID:26084804
  • Anderson MS, Casanova JL. More than Meets the Eye: Monogenic Autoimmunity Strikes Again. Immunity. 2015 Jun 16;42(6):986-8. doi: 10.1016/j.immuni.2015.06.004. PMID:26084018
  • Bluestone JA, Bour-Jordan H, Cheng M, Anderson M. T cells in the control of organ-specific autoimmunity. J Clin Invest. 2015 Jun;125(6):2250-60. doi: 10.1172/JCI78089. Epub 2015 May 18. Review. PMID:25985270 | PMCID:PMC4497750
  • Watkin LB, Jessen B, Wiszniewski W, Vece TJ, Jan M, Sha Y, Thamsen M, Santos-Cortez RL, Lee K, Gambin T, Forbes LR, Law CS, Stray-Pedersen A, Cheng MH, Mace EM, Anderson MS, Liu D, Tang LF, Nicholas SK, Nahmod K, Makedonas G, Canter DL, et al. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis. Nat Genet. 2015 Jun;47(6):654-60. doi: 10.1038/ng.3279. Epub 2015 Apr 20. PMID:25894502 | PMCID:PMC4513663
  • Su MA, Anderson MS. Breaking through the central tolerance ceiling to unleash anticancer immune responses. Oncoimmunology. 2014 Aug 3;3(8):e950169. eCollection 2014. PMID:25610739 | PMCID:PMC4292738
  • Hardtke-Wolenski M, Taubert R, Noyan F, Sievers M, Dywicki J, Schlue J, Falk CS, Ardesjö Lundgren B, Scott HS, Pich A, Anderson MS, Manns MP, Jaeckel E. Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens. Hepatology. 2015 Apr;61(4):1295-305. doi: 10.1002/hep.27639. Epub 2015 Feb 24. PMID:25475693
  • Anderson MS. Too much of a good thing: NLRC4 and autoinflammation. J Exp Med. 2014 Nov 17;211(12):2329. doi: 10.1084/jem.21112insight5. No abstract available. PMID:25403807 | PMCID:PMC4235639
  • Khan IS, Mouchess ML, Zhu ML, Conley B, Fasano KJ, Hou Y, Fong L, Su MA, Anderson MS. Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance. J Exp Med. 2014 May 5;211(5):761-8. doi: 10.1084/jem.20131889. Epub 2014 Apr 21. PMID:24752296 | PMCID:PMC4010907
  • Chen YF, Zhou D, Metzger T, Gallup M, Jeanne M, Gould DB, Anderson MS, McNamara NA. Spontaneous development of autoimmune uveitis Is CCR2 dependent. Am J Pathol. 2014 Jun;184(6):1695-705. doi: 10.1016/j.ajpath.2014.02.024. Epub 2014 Apr 13. PMID:24736166 | PMCID:PMC4044718
  • Khan IS, Taniguchi RT, Fasano KJ, Anderson MS, Jeker LT. Canonical microRNAs in thymic epithelial cells promote central tolerance. Eur J Immunol. 2014 May;44(5):1313-9. doi: 10.1002/eji.201344079. Epub 2014 Mar 20. PMID:24515814 | PMCID:PMC4141217
  • Waterfield M, Khan IS, Cortez JT, Fan U, Metzger T, Greer A, Fasano K, Martinez-Llordella M, Pollack JL, Erle DJ, Su M, Anderson MS. The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. Nat Immunol. 2014 Mar;15(3):258-65. doi: 10.1038/ni.2820. Epub 2014 Jan 26. Erratum in: Nat Immunol. 2014 Sep;15(9):894. PMID:24464130 | PMCID:PMC4172453
  • Price JV, Haddon DJ, Kemmer D, Delepine G, Mandelbaum G, Jarrell JA, Gupta R, Balboni I, Chakravarty EF, Sokolove J, Shum AK, Anderson MS, Cheng MH, Robinson WH, Browne SK, Holland SM, Baechler EC, Utz PJ. Protein microarray analysis reveals BAFF-binding autoantibodies in systemic lupus erythematosus. J Clin Invest. 2013 Dec;123(12):5135-45. doi: 10.1172/JCI70231. Epub 2013 Nov 25. PMID:24270423 | PMCID:PMC3859403
  • Mohan JF, Calderon B, Anderson MS, Unanue ER. Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes. J Exp Med. 2013 Oct 21;210(11):2403-14. doi: 10.1084/jem.20130582. Epub 2013 Oct 14. PMID:24127484 | PMCID:PMC3804950
  • Shum AK, Alimohammadi M, Tan CL, Cheng MH, Metzger TC, Law CS, Lwin W, Perheentupa J, Bour-Jordan H, Carel JC, Husebye ES, De Luca F, Janson C, Sargur R, Dubois N, Kajosaari M, Wolters PJ, Chapman HA, Kämpe O, Anderson MS. BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Sci Transl Med. 2013 Oct 9;5(206):206ra139. doi: 10.1126/scitranslmed.3006998. PMID:24107778 | PMCID:PMC3882146
  • Metzger TC, Khan IS, Gardner JM, Mouchess ML, Johannes KP, Krawisz AK, Skrzypczynska KM, Anderson MS. Lineage tracing and cell ablation identify a post-Aire-expressing thymic epithelial cell population. Cell Rep. 2013 Oct 17;5(1):166-79. doi: 10.1016/j.celrep.2013.08.038. Epub 2013 Oct 3. PMID:24095736 | PMCID:PMC3820422
  • Schafer AL, Mumm S, El-Sayed I, McAlister WH, Horvai AE, Tom AM, Hsiao EC, Schaefer FV, Collins MT, Anderson MS, Whyte MP, Shoback DM. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. J Bone Miner Res. 2014 Apr;29(4):911-21. doi: 10.1002/jbmr.2094. PMID:24014458 | PMCID:PMC4419358
  • Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity. 2013 Sep 19;39(3):560-72. doi: 10.1016/j.immuni.2013.08.005. Epub 2013 Aug 29. PMID:23993652 | PMCID:PMC3804105
  • Cheng MH, Anderson MS. Insights into type 1 diabetes from the autoimmune polyendocrine syndromes. Curr Opin Endocrinol Diabetes Obes. 2013 Aug;20(4):271-8. doi: 10.1097/MED.0b013e32836313eb. Review. PMID:23770732 | PMCID:PMC4165040
  • Oh J, Wu N, Baravalle G, Cohn B, Ma J, Lo B, Mellman I, Ishido S, Anderson M, Shin JS. MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells. J Exp Med. 2013 Jun 3;210(6):1069-77. doi: 10.1084/jem.20122695. Epub 2013 May 27. PMID:23712430 | PMCID:PMC3674695
  • Parent AV, Russ HA, Khan IS, LaFlam TN, Metzger TC, Anderson MS, Hebrok M. Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development. Cell Stem Cell. 2013 Aug 1;13(2):219-29. doi: 10.1016/j.stem.2013.04.004. Epub 2013 May 16. PMID:23684540 | PMCID:PMC3869399
  • Taniguchi RT, DeVoss JJ, Moon JJ, Sidney J, Sette A, Jenkins MK, Anderson MS. Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7847-52. doi: 10.1073/pnas.1120607109. Epub 2012 May 2. PMID:22552229 | PMCID:PMC3356674
  • Su MA, Davini D, Cheng P, Giang K, Fan U, DeVoss JJ, Johannes KP, Taylor L, Shum AK, Valenzise M, Meloni A, Bour-Jordan H, Anderson MS. Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy. J Immunol. 2012 May 15;188(10):4906-12. doi: 10.4049/jimmunol.1200493. Epub 2012 Apr 6. PMID:22490868 | PMCID:PMC3579634
  • Cheng MH, Anderson MS. Monogenic autoimmunity. Annu Rev Immunol. 2012;30:393-427. doi: 10.1146/annurev-immunol-020711-074953. Epub 2012 Jan 6. Review. PMID:22224765 | PMCID:PMC6249029
  • Waterfield M, Anderson MS. Autoimmunity's collateral damage: Immunodeficiency hints at autoreactivity to cytokines. Nat Med. 2011 Sep 7;17(9):1054-5. doi: 10.1038/nm0911-1054. No abstract available. PMID:21900922
  • Metzger TC, Anderson MS. Control of central and peripheral tolerance by Aire. Immunol Rev. 2011 May;241(1):89-103. doi: 10.1111/j.1600-065X.2011.01008.x. Review. PMID:21488892 | PMCID:PMC3093413
  • Metzger TC, Anderson MS. Myocarditis: a defect in central immune tolerance? J Clin Invest. 2011 Apr;121(4):1251-3. doi: 10.1172/JCI57211. Epub 2011 Mar 23. PMID:21436581 | PMCID:PMC3069797
  • Anderson MS, Su MA. Aire and T cell development. Curr Opin Immunol. 2011 Apr;23(2):198-206. doi: 10.1016/j.coi.2010.11.007. Epub 2010 Dec 14. Review. PMID:21163636 | PMCID:PMC3073725
  • Taniguchi RT, Anderson MS. The role of Aire in clonal selection. Immunol Cell Biol. 2011 Jan;89(1):40-4. doi: 10.1038/icb.2010.132. Epub 2010 Nov 16. Review. PMID:21079643 | PMCID:PMC3017232
  • Waterfield M, Anderson MS. Clues to immune tolerance: the monogenic autoimmune syndromes. Ann N Y Acad Sci. 2010 Dec;1214:138-55. doi: 10.1111/j.1749-6632.2010.05818.x. Epub 2010 Oct 22. Review. PMID:20969580 | PMCID:PMC3010261
  • Husebye ES, Anderson MS. Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis. Immunity. 2010 Apr 23;32(4):479-87. doi: 10.1016/j.immuni.2010.03.016. Review. PMID:20412758 | PMCID:PMC2859971
  • Shum AK, DeVoss J, Tan CL, Hou Y, Johannes K, O'Gorman CS, Jones KD, Sochett EB, Fong L, Anderson MS. Identification of an autoantigen demonstrates a link between interstitial lung disease and a defect in central tolerance. Sci Transl Med. 2009 Dec 2;1(9):9ra20. doi: 10.1126/scitranslmed.3000284. PMID:20368189 | PMCID:PMC2856693
  • DeVoss JJ, LeClair NP, Hou Y, Grewal NK, Johannes KP, Lu W, Yang T, Meagher C, Fong L, Strauss EC, Anderson MS. An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse. J Immunol. 2010 Apr 15;184(8):4236-46. doi: 10.4049/jimmunol.0902434. Epub 2010 Mar 17. PMID:20237294 | PMCID:PMC2851482
  • Cheng MH, Fan U, Grewal N, Barnes M, Mehta A, Taylor S, Husebye ES, Murphy EJ, Anderson MS. Acquired autoimmune polyglandular syndrome, thymoma, and an AIRE defect. N Engl J Med. 2010 Feb 25;362(8):764-6. doi: 10.1056/NEJMc0909510. No abstract available. PMID:20181983 | PMCID:PMC3462012
  • Gardner JM, Fletcher AL, Anderson MS, Turley SJ. AIRE in the thymus and beyond. Curr Opin Immunol. 2009 Dec;21(6):582-9. doi: 10.1016/j.coi.2009.08.007. Epub 2009 Oct 14. Review. PMID:19833494 | PMCID:PMC2787634
  • Gardner JM, Anderson MS. The sickness unto Deaf. Nat Immunol. 2009 Sep;10(9):934-6. doi: 10.1038/ni0909-934. PMID:19692991 | PMCID:PMC2773699
  • Hou Y, DeVoss J, Dao V, Kwek S, Simko JP, McNeel DG, Anderson MS, Fong L. An aberrant prostate antigen-specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans. J Clin Invest. 2009 Jul;119(7):2031-41. doi: 10.1172/JCI38332. PMID:19603556 | PMCID:PMC2701875
  • Louvet C, Kabre BG, Davini DW, Martinier N, Su MA, DeVoss JJ, Rosenthal WL, Anderson MS, Bour-Jordan H, Bluestone JA. A novel myelin P0-specific T cell receptor transgenic mouse develops a fulminant autoimmune peripheral neuropathy. J Exp Med. 2009 Mar 16;206(3):507-14. doi: 10.1084/jem.20082113. Epub 2009 Feb 16. PMID:19221395 | PMCID:PMC2699118
  • Su MA, Anderson MS. Monogenic autoimmune diseases: insights into self-tolerance. Pediatr Res. 2009 May;65(5 Pt 2):20R-25R. doi: 10.1203/PDR.0b013e31819dc55c. Review. PMID:19190526 | PMCID:PMC2951117
  • Su MA, Stenerson M, Liu W, Putnam A, Conte F, Bluestone JA, Anderson MS. The role of X-linked FOXP3 in the autoimmune susceptibility of Turner Syndrome patients. Clin Immunol. 2009 Apr;131(1):139-44. doi: 10.1016/j.clim.2008.11.007. Epub 2009 Jan 15. PMID:19150256 | PMCID:PMC2949956
  • Anderson MS. Update in endocrine autoimmunity. J Clin Endocrinol Metab. 2008 Oct;93(10):3663-70. doi: 10.1210/jc.2008-1251. Review. PMID:18842982 | PMCID:PMC2579640
  • Devoss JJ, Shum AK, Johannes KP, Lu W, Krawisz AK, Wang P, Yang T, Leclair NP, Austin C, Strauss EC, Anderson MS. Effector mechanisms of the autoimmune syndrome in the murine model of autoimmune polyglandular syndrome type 1. J Immunol. 2008 Sep 15;181(6):4072-9. PMID:18768863 | PMCID:PMC2556863
  • Zhou X, Jeker LT, Fife BT, Zhu S, Anderson MS, McManus MT, Bluestone JA. Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity. J Exp Med. 2008 Sep 1;205(9):1983-91. doi: 10.1084/jem.20080707. Epub 2008 Aug 25. PMID:18725525 | PMCID:PMC2526194
  • Gardner JM, Devoss JJ, Friedman RS, Wong DJ, Tan YX, Zhou X, Johannes KP, Su MA, Chang HY, Krummel MF, Anderson MS. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science. 2008 Aug 8;321(5890):843-7. doi: 10.1126/science.1159407. PMID:18687966 | PMCID:PMC2532844
  • Su MA, Giang K, Zumer K, Jiang H, Oven I, Rinn JL, Devoss JJ, Johannes KP, Lu W, Gardner J, Chang A, Bubulya P, Chang HY, Peterlin BM, Anderson MS. Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire. J Clin Invest. 2008 May;118(5):1712-26. doi: 10.1172/JCI34523. PMID:18414681 | PMCID:PMC2293336
  • Schaller CE, Wang CL, Beck-Engeser G, Goss L, Scott HS, Anderson MS, Wabl M. Expression of Aire and the early wave of apoptosis in spermatogenesis. J Immunol. 2008 Feb 1;180(3):1338-43. PMID:18209027
  • Li S, Nikulina K, DeVoss J, Wu AJ, Strauss EC, Anderson MS, McNamara NA. Small proline-rich protein 1B (SPRR1B) is a biomarker for squamous metaplasia in dry eye disease. Invest Ophthalmol Vis Sci. 2008 Jan;49(1):34-41. doi: 10.1167/iovs.07-0685. PMID:18172072 | PMCID:PMC2574421
  • Zhang L, Barker JM, Babu S, Su M, Stenerson M, Cheng M, Shum A, Zamir E, Badolato R, Law A, Eisenbarth GS, Anderson MS. A robust immunoassay for anti-interferon autoantibodies that is highly specific for patients with autoimmune polyglandular syndrome type 1. Clin Immunol. 2007 Nov;125(2):131-7. Epub 2007 Sep 6. PMID:17825626 | PMCID:PMC2080870
  • Cheng MH, Shum AK, Anderson MS. What's new in the Aire? Trends Immunol. 2007 Jul;28(7):321-7. Epub 2007 Jun 7. Review. PMID:17556019
  • DeVoss JJ, Anderson MS. Lessons on immune tolerance from the monogenic disease APS1. Curr Opin Genet Dev. 2007 Jun;17(3):193-200. Epub 2007 Apr 26. Review. PMID:17466510
  • DeVoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi RR, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen. J Exp Med. 2006 Nov 27;203(12):2727-35. Epub 2006 Nov 20. Erratum in: J Exp Med. 2007 Jan 22;204(1):203. Caspi, Rachel [corrected to Caspi, Rachel R]. PMID:17116738 | PMCID:PMC2118158
  • Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Pociot F, Todd JA, Rich SS; Type 1 Diabetes Genetics Consortium.. Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families. Diabetes. 2005 Oct;54(10):2995-3001. PMID:16186404
  • Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C. Modifier loci condition autoimmunity provoked by Aire deficiency. J Exp Med. 2005 Sep 19;202(6):805-15. PMID:16172259 | PMCID:PMC2212943
  • Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity. 2005 Aug;23(2):227-39. PMID:16111640
  • Anderson MS, Bluestone JA. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol. 2005;23:447-85. Review. PMID:15771578
  • Su MA, Anderson MS. Aire: an update. Curr Opin Immunol. 2004 Dec;16(6):746-52. Review. PMID:15511668
  • Anderson MS. Autoimmune endocrine disease. Curr Opin Immunol. 2002 Dec;14(6):760-4. PMID:12413526
  • Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science. 2002 Nov 15;298(5597):1395-401. Epub 2002 Oct 10. PMID:12376594
  • Anderson MS, Brogi E, Biller BM. Occult Leydig cell tumor in a patient with gynecomastia. Endocr Pract. 2001 Jul-Aug;7(4):267-71. PMID:11497478
  • Anderson MS, Swier K, Arneson L, Miller J. Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal. J Exp Med. 1993 Dec 1;178(6):1959-69. PMID:7902408 | PMCID:PMC2191285
  • Naujokas MF, Morin M, Anderson MS, Peterson M, Miller J. The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44. Cell. 1993 Jul 30;74(2):257-68. PMID:8343954
  • Anderson MS, Miller J. Invariant chain can function as a chaperone protein for class II major histocompatibility complex molecules. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2282-6. PMID:1549594 | PMCID:PMC48641
  • Lakey EK, Casten LA, Anderson MS, Smolenski LA, Smith JA, Margoliash E, Pierce SK. T cell activation by processed antigen is equally blocked by I-E and I-A-restricted immunodominant peptides. Eur J Immunol. 1987 Nov;17(11):1605-9. PMID:3500065